Living Organisms
Sigma Aldrich Fine Chemicals Biosciences Hirudin from leeches lyoph
Hirudin is a 7 kDa acidic protein containing 65 amino acid residues that has an isoelectric point of 3.5-4.0. It is not glycosylated and lacks tryptophan arginine and methionine residues. It is chemically stable between pH 2-12 and at temperatures up to 80C.
Cayman Chemical Cefotiam (hydrochloride hydrate), Purity: ≥80%, 1 g
A broad-spectrum cephalosporin antibiotic; inhibits the growth of S. aureus (MIC50 = 0.26 µg/ml), as well as P. aeruginosa, E. coli, and H. influenzae (MIC50s = 1, 0.06, and 0.01 µg/ml, respectively); increases survival in mouse models of infection with strains of S. aureus (ED50s = 3.5 and 8.3 mg/kg) and E. coli (ED50s = 0.5-25 mg/kg)
Cayman Chemical Clodronate (sodium salt hydrate), Purity: ≥95%, CAS: 88416-50-6, 10 mg
A non-nitrogenous bisphosphonate that inhibits hydroxyapatite crystal growth (IC50 = 1.34 µM) and bone resorption; is cytotoxic to both osteoclasts and macrophages and has been used in biological research to selectively induce apoptosis of macrophage-like cells and cancer cells
Cayman Chemical Cefepime (hydrochloride hydrate), Purity: ≥90%, CAS: 123171-59-5, 5 g
A cephalosporin antibiotic; inhibits the growth of some clinical isolates of Corynebacterium, Streptococcus, and Staphylococcus (MIC90s = 0.03-8 μg/ml); inhibits the growth of some Citrobacter, Enterobacter, Klebsiella, Salmonella, Serratia, Shigella, and enteric bacilli species in addition to P. mirabilis and E. coli clinical isolates (MIC90s = ≤0.12-2 μg/ml); inhibits the growth of pneumococci strains (MICs = 0.5-2 mg/l) in vitro and in vivo in a mouse model of peritonitis (ED50s = 0.6-1.14 mg/kg)
Cayman Chemical Harmalol (hydrochloride hydrate), Purity: ≥98%, CAS: 6028-00-8, 500 mg
A β-carboline alkaloid and an active metabolite of harmaline; an inhibitor of DYRK1A (IC50 = 0.63 µM); an inhibitor of MAO-A (IC50 = 0.66 µM); selective for DYRK1A over Cdk1, Cdk5, CK1α1, Clk4, DYRK2, Pim-1, and GSK3β but also inhibits DYRK1B and Clk1 at 10 µM; inhibits proliferation of H4 human glioblastoma cells (IC50s = 23.7 µM); reduces TCDD-induced increases in CYP1A1 levels in HepG2 cells and prevents TCDD-induced activation of AhR in guinea pig hepatic cytosolic extracts; reduces glutamate-induced cytotoxicity, cytochrome c release, caspase-3 activation, and ROS production in PC12 cells at 25 µM
TRIBIOSCIENCE INC Escherichia coli (E. Coli) - Salmonella qPCR Kit, 100 Tests
The Escherichia Coli (E. Coli)-Salmonella Multiple qPCR Kit provides a fast, accurate, and simple approach to detecting E. coli and salmonella contamination of food ingredients, cannabis products, water, environmental samples, or other biosamples.
Cayman Chemical Enniatin B, Purity: ≥95%, CAS: 917-13-5, 1 mg
Inhibits the Pdr5p in yeast, augmenting, at concentrations as low as 0.8 μM, the ability of cerulenin or cycloheximide to impair cell proliferation; inhibits ACAT (IC50 = 113 μM), blocking cholesteryl ester formation
Cayman Chemical A-943931 (hydrochloride hydrate), Purity: ≥98%, 1 mg
A histamine H4 receptor antagonist (Ki = 3.8 nM); inhibits clobenpropit-induced scratching in mice (ED50 = 26 µmoles/kg, i.p.)
Enterprise Technology Solutions Learning Resources Garden Set,Hide/Seek,Veggies/Bunny,Multicolor
Hide and Seek Vegetable Garden lets children discover new counting, color and memory skills as they search for the funny bunny. As children search the pots for the hidden bunny, they will also use this preschool toy to strengthen their memory and critical-thinking skills. Each piece is made with recycled plastic as a sustainable way to learn, play and grow. Game also includes an activity guide filled with child-friendly sustainability facts and preschool learning activities that help children discover new ways to keep things green. Set includes five pots, four vegetables and one fun bunny. Learning toy is perfect for children ages 18 months and older.
Cayman Chemical Frovatriptan (succinate hydrate), Purity: ≥98%, CAS: 158930-17-7, 50 mg
An agonist of 5-HT1B and 5-HT1D receptors (Kis = 2.51 and 3.98 nM, respectively); selective for 5-HT1B and 5-HT1D over 5-HT1A, 5-HT1E, 5-HT1F, 5-HT2A, 5-HT2C, 5-HT3, and 5-HT7 receptors, as well as dopamine D1, D2, and D3, histamine H1, and α1-adrenergic receptors (Kis = >50 nM); induces contractions in human basilar arteries isolated post-mortem, coronary arteries from transplant recipient hearts, and coronary arteries from donor hearts unsuitable for transplantation (EC50s = 13.8, 41.69, and 15.49 nM, respectively); increases carotid vascular resistance in closed-chest and open-chest anesthetized dogs (ED50s = 6 and 1 nmol/kg, i.v., respectively)
Enterprise Technology Solutions Learning Resources Primary Science Big View Bug Jars, 6/ST, Ast
Adorable jars feature ladybug wings that open to invite little learners to investigate insects. The wings open up to reveal the 3.5X magnifying lens to let students take a closer look. Cute, secure design engages even children who normally shy away from bugs to observe critters. Air vents in the plastic jar allow live-critter observations. Bug jars are designed for children ages 3 and up.